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CANCER, WARTS, AND SUNSHINE IN RENAL TRANSPLANT PATIENTS

Identifieur interne : 002524 ( Main/Exploration ); précédent : 002523; suivant : 002525

CANCER, WARTS, AND SUNSHINE IN RENAL TRANSPLANT PATIENTS

Auteurs : J. Boyle [Royaume-Uni] ; J. D. Briggs [Royaume-Uni] ; Ronam. Mackie [Royaume-Uni] ; B. J. R. Junor [Royaume-Uni] ; T. C. Aitchison [Royaume-Uni]

Source :

RBID : ISTEX:AFD5593EDFEF745AA526D92DE97D6A814A604024

English descriptors

Abstract

Abstract: 94 renal transplant patients were examined for the presence of cutaneous malignancies, actinic keratoses, warts, and cutaneous fungal infection, and a history was taken of infection with herpes simplex and herpes zoster. Each patient had a control matched for age, sex, and sun exposure. Of the 17 patients with high exposure to sunshine (more than 3 months in a tropical or subtropical climate or more than 5 years in an outdoor occupation), 2 had squamous cell carcinoma and 7 actinic keratoses. These lesions did not occur in the other renal transplant patients or the control group. The immunosuppressive effect of ultraviolet radiation in the sunburn spectrum (290-320 nm) in man and animals may be related to the increased incidence of cutaneous malignancy, actinic keratoses, and warts. Transplant patients should be under regular surveillance for the early detection and treatment of premalignant cutaneous lesions, and they should receive advice on avoiding sun exposure.

Url:
DOI: 10.1016/S0140-6736(84)92221-9


Affiliations:


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Le document en format XML

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<term>Actinic</term>
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<term>Alternate days</term>
<term>Attenuated</term>
<term>Attenuated influenza</term>
<term>Carcinoma</term>
<term>Cell carcinoma</term>
<term>Common warts</term>
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<term>Epidermodysplasia verruciformis</term>
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<term>High incidence</term>
<term>Immune</term>
<term>Immune system</term>
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<term>Immunosuppressive</term>
<term>Immunosuppressive drugs</term>
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<term>Infectious diseases</term>
<term>Influenza</term>
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<term>Leukocyte reaction</term>
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<term>Malignant</term>
<term>Monoclonal antibodies</term>
<term>Peripheral blood</term>
<term>Pneumocystis carinii pneumonia</term>
<term>Premalignant cutaneous lesions</term>
<term>Premalignant lesions</term>
<term>Protective efficacy</term>
<term>Reassortant</term>
<term>Reassortant virus</term>
<term>Reassortant viruses</term>
<term>Renal</term>
<term>Renal transplant patients</term>
<term>Renal transplant recipients</term>
<term>Renal transplants</term>
<term>Simplex</term>
<term>Skin cancer</term>
<term>Squamous</term>
<term>Squamous cell carcinoma</term>
<term>Squamous cell carcinomas</term>
<term>Subtropical climate</term>
<term>Suppressor</term>
<term>Suppressor lymphocyte subsets</term>
<term>Surface markers</term>
<term>Transplant</term>
<term>Transplant patients</term>
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<term>Transplantation</term>
<term>Tumour</term>
<term>Tumour rejection</term>
<term>Ultraviolet irradiation</term>
<term>Ultraviolet radiation</term>
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<div type="abstract" xml:lang="en">Abstract: 94 renal transplant patients were examined for the presence of cutaneous malignancies, actinic keratoses, warts, and cutaneous fungal infection, and a history was taken of infection with herpes simplex and herpes zoster. Each patient had a control matched for age, sex, and sun exposure. Of the 17 patients with high exposure to sunshine (more than 3 months in a tropical or subtropical climate or more than 5 years in an outdoor occupation), 2 had squamous cell carcinoma and 7 actinic keratoses. These lesions did not occur in the other renal transplant patients or the control group. The immunosuppressive effect of ultraviolet radiation in the sunburn spectrum (290-320 nm) in man and animals may be related to the increased incidence of cutaneous malignancy, actinic keratoses, and warts. Transplant patients should be under regular surveillance for the early detection and treatment of premalignant cutaneous lesions, and they should receive advice on avoiding sun exposure.</div>
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